Parshas Mikeitz: Megaleh Amukos - A Long Time To Suffer
After getting a very unfriendly welcome from Yosef, the pasuk says (Mikeitz 42:21), "Vayomru Ish El Achiv Aval Asheimim Anachnu; The brothers said indeed we are guilty as we saw the pain of our brother Yosef, and ignored his pleas."
The Shnayim Mikra brings from the Megaleh Amukos that six consecutive words starting with Ish, begin with the letter Aleph. These six Alephs each represent one millennium of the world's six thousand years of existence. The Torah is telling us that the mistake of selling Yosef will haunt us throughout the entire history.